Applications are invited for a fully-funded 4-year PhD studentship based in the Department of Pathology at the University of Cambridge under the supervision of Dr Betty Chung (https://www.path.cam.ac.uk/directory/betty-chung) starting October 2025.
Biotic stresses often unfold rapidly, demanding swift responses from both host and pathogen to ensure survival. Upon their encounter, a sophisticated network of gene regulation is instantly activated in both organisms, spanning transcription, translation, and protein turnover. While transcriptional regulation offers versatility, translational control enables potent, efficient and rapid adjustment in protein abundance, which is crucial during the initial stages of infection for both host and pathogen. This project seeks to unravel the intricate translational regulatory mechanisms governing host-pathogen interactions, aiming to decode the molecular dynamics and triggers that influence virulence, pathogenicity, and innate immunity.
Please visit https://www.path.cam.ac.uk/graduate/fully-funded-studentships for a more detailed description of the project and application.