Dr Indra Roux
Postdoctoral Researcher
MRC Toxicology Unit
Biography
Indra Roux studied Biotechnology at the National University of Quilmes (Argentina). Following her interest in engineering microbial metabolism, she obtained a PhD at The University of Western Australia (Australia) in 2021, with a subsequent postdoc. In 2022 she joined the MRC Toxicology Unit as a postdoctoral researcher at Kiran Patil’s lab, where she is advancing genetic screens in unconventional gut bacteria to investigate chemical and ecological interactions. She is also a postdoctoral representative at the Engineering Biology IRC Cambridge.
Research
I am fascinated by the vastly under-explored microbial metabolism, and how synthetic biology can help us investigate it and unlock its potential. At MRC Toxicology Unit, I aim to explore the mechanisms and genetic basis behind the interactions between gut microbes and xenobiotic compounds, as well as interspecies metabolic interactions. Xenobiotics present in medications, food or environmental pollutants can interact with bacteria and impact their growth and metabolism. On the other hand, xenobiotic compounds can also be metabolised or accumulated by bacteria. Advancing the molecular mechanisms behind these interactions is critical to predict the effects of xenobiotics in the microbiome of an individual and develop diagnostics and health solutions. To this end, I plan to expand the genetic and synthetic biology toolbox for under-explored gut bacteria, allowing us to interrogate them at a genome scale.
