Prof. Mark Howarth

Professor Mark HowarthSheild Chair of PharmacologyDepartment of PharmacologyBiography

Mark Howarth is the Sheild Professor in Cambridge University Department of Pharmacology. He co-founded the company SpyBiotech and has been awarded the Royal Society of Chemistry Norman Heatley Award. He did postdoctoral studies at MIT with Alice Ting, where he developed monovalent streptavidin and single molecule probes for tracking neurotransmitter receptors. His doctoral work was with Tim Elliott at Southampton University on MHC class I-peptide quality control. His current work is on innovating ultra-stable protein interactions through peptide superglues, NeissLock and gastrobodies. These tools are being applied to vaccine development, cell therapy and cancer targeting.

Research

The theme of our group's research is innovating protein technologies for therapeutics and vaccine design. Inspired by extraordinary molecular features from the natural world, our research develops new approaches for disease prevention and therapy. By engineering and evolving proteins and cellular systems, our projects range from fundamental analysis of protein interactions through to clinical application. Please see www.howarthgroup.org for further information.